The baby’s metabolism depends on a healthy diet during breastfeeding

a Healthy diet During the lactation period, it manages to normalize the lipid content (concentrations of various types of fat) in breast milk and prevent metabolic changes in the offspring. This is confirmed by a recent study carried out by a team from the Obesity and Nutrition Area of ​​the Online Biomedical Research Center (Cyberoban) of the University of the Balearic Islands (UIB) and the Health Research Institute of the Balearic Islands. . Islands (Idisba), in collaboration with the Institute of Physiology of the Czech Academy of Sciences. The results have been published in the journal Research in Molecular Nutrition and Food,

Through this study, we sought to assess, in an animal model, whether normalizing the maternal diet during lactation could prevent the deleterious effects of an obesogenic diet (which is common in humans) before and during pregnancy. promotes obesity). Or the lipidomic profile (a set of hundreds of lipids) in the milk and plasma of the offspring, and it turned out that it is possible to obtain it.

This new knowledge is relevant because, in addition to the existing evidence on the importance of the nutritional environment during fetal life for the correct development and subsequent health of the offspring, it shows that the recovery of a healthy maternal diet during lactation can be prevented. it is, at least in part, metabolic disorders in the offspring caused by poor diet and obesity during the prenatal stages.

Leading the obesity and nutrition team, Andre Palu and Catalina Pico. Photo: AC/UIB.

chronic pathology

Previous interventional studies in animal models have shown that consumption of an obesogenic diet during the perinatal period affects mammary gland function and thus milk composition, meaning that these changes “program” the mother. offspring for a higher propensity. It can in adulthood develop chronic pathology. Based on this, the researchers found it interesting to study possible intervention strategies during the lactation period to prevent adverse effects caused by an unbalanced maternal diet during or even before pregnancy. To do this, they analyzed lipidomic profiles to determine the changes that may be involved in the risk of developing diseases for pups in later stages, as well as analyzes of plasma profiles of pups in the last stages of lactation. can also do.

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The results of this study showed that maternal consumption of an obesogenic diet during the perinatal period (specifically, one month before pregnancy and during pregnancy and lactation) caused a significant change in the lipid composition of milk and plasma of their babies. causes preliminary stage. These changes were largely reversed in the milk of mothers who received a balanced diet during lactation and in the plasma of their offspring. The authors of the study, led by Dr. Catalina Pico, are now studying the extent to which these results (obtained in an animal model) can be extrapolated to humans. In any case, they recommend extreme care in feeding during lactation, as a critical period in which it is possible to correct metabolic changes in the offspring.